MANZO, Ciro. Questions as regards the recognition of elderly-onset primary Sjögren's syndrome: Where we are and where we would rather be. []. , 27, 2, pp.75-81.   06--2021. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.05.006.

Several epidemiological studies have suggested that the prevalence of the onset of primary Sjögren's Syndrome in the elderly (EOpSS) is significantly higher (between five to eight times) than in other age groups. However, when a literature review was performed, the number of patients with EOpSS was much lower than epidemiologically expected. An evaluation was performed on Sjögren (sicca) syndrome, including immunological markers, labial salivary glands biopsy, and some extra-glandular manifestations. These could be confounding factors in the elderly patients, much more so than in other age groups, and lead to a misdiagnosis of EOpSS. This article presents a review of the most common difficulties that may be present in the recognition of EOpSS, and highlights the lack of elderly patient-centred studies as the most important unmet need.

: Primary Sjögren's syndrome; Elderly-onset primary Sjögren's; syndrome; Elderly patients; Drug-induced sicca syndrome; Classification criteria.

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