RODRIGUEZ-PINTO, Ignasi; LOPEZ-BENJUME, Brenda; ESPINOSA, Gerard    CERVERA, Ricard. Catastrophic antiphospholipid syndrome. []. , 28, 1, pp.39-43.   17--2022. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2021.02.004.

The antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by the development of thrombotic events and/or obstetric morbidity in the presence of antiphospholipid antibodies (aPL), such as the lupus anticoagulant (LA), anticardiolipin antibodies (aCL) or anti- β 2-glycoprotein I antibodies (a β2 GPI). In 1992, Ronald A. Asherson described a very aggressive clinical variant of this syndrome characterized by the development of multiple thrombotic manifestations, simultaneously or in a short period of time. The term catastrophic APS was proposed and since then it is known by this name.

: Antiphospholipid syndrome; Catastrophic antiphospholipid syndrome; Antiphospholipid antibodies.

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