Abstract

GONZALEZ NARANJO, Luis Alonso; VASQUEZ, Gloria María  and  RAMIREZ GOMEZ, Luis Alberto. End-Stage Renal Disease in Systemic Lupus Erythematosus. Rev.Colomb.Reumatol. [online]. 2009, vol.16, n.2, pp.167-182. ISSN 0121-8123.

End-stage renal disease (ESRD) occurs in 5%-20% of all systemic lupus erythematosus (SLE) patients within 10 years after diagnosis of lupus nephritis (LN). Both clinical and serological lupus activities decrease or dramatically improve once ESRD ensues. The survival rate of lupus patients on dialysis is comparable to that of the non-SLE dialysis patients and is better than that of several other rheumatic diseases. Following renal transplantation, there is no difference in patient and graft survival in lupus versus non-lupus patients. Like their non-lupus counterparts, SLE transplant patients do better with living relative grafts. The recurrence rate of LN in transplanted allografts is low and rarely responsible for graft loss.

Keywords : systemic lupus erythematosus; lupus nephritis; end-stage renal disease.

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