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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
REINA AVILA, María Fernanda and MALAGON, Clara. Health-related quality of life in adults with juvenile idiopathic arthritis. Rev.Colomb.Reumatol. [online]. 2020, vol.27, n.1, pp.26-36. Epub Dec 13, 2020. ISSN 0121-8123.
Background:
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in the paediatric age. It is estimated that between 30-60% of adults patients persist with active disease, which leads to sequelae and complications as well as a decrease functional capacity and reduced quality of life.
Objectives:
To evaluate the health-related quality of life in adult patients diagnosed with juvenile idiopathic arthritis.
Methodology:
A cross-sectional study was performed, using a search for adult patients diagnosed with JIA between 1996 and 2018. Clinical records were reviewed during the paediatric age, and clinical parameters were evaluated for activity (JADASc-71), and joint (JADI-A) and extra-articular (JADI-E) damage, functional capacity (HAQ), and quality of life (SF-36). Relationships were determined by non-conditional logistic regression.
Results:
A total of 69 patients were included. The most frequent subtype of JIA was enthesitis-related arthritis (ERA) (33%). Active disease was observed in 33%. Polyarticular JIA RF (+) was associated with active disease (P = .007), high values of JADASc-71 (P = .003), and HAQ (P = .001). Age of onset after 5 years reduced risk of joint damage (OR = 0.16) and extra-articular damage (OR = 0.03). Poor therapeutic adherence was associated with joint damage (P = .00) and JADASc-71 (P = .004). A high score of JADI-E was associated with functional dis-ability (OR = 5.75). Joint damage (P = .003) and extra-articular damage (P = .024), and functional disability (OR = 7.05) were associated with low values in the SF-36.
Conclusions:
JIA is not a disease limited to the paediatric age. Persistence of active disease, joint, and extra-articular damage are associated with functional disability and a decrease in H-RQoL.
Keywords : Juvenile idiopathic arthritis; Adults; Active disease; Joint damage; Extra-Joint damage; Health-Related quality of life.