Abstract

MEDINA, Yimy F.  and  MEDINA TORRES, Daniel. Renal involvement in scleroderma. Rev.Colomb.Reumatol. [online]. 2020, vol.27, suppl.1, pp.55-61.  Epub Aug 21, 2021. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.03.005.

Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by vasculopathy, inflammation, collagen deposits and fibrosis in the skin and internal organs. Renal complications are common in SSc. The spectrum of renal complications in systemic sclerosis includes scleroderma renal crisis (SRC), abnormal renal function, proteinuria, renal chronic vascular disease, kidney injury from nephrotoxic drugs, oxalate calcium nephropathy, glomerulonephritis and vasculitis associated to anti-neutrophil cytoplasmic antibody. Renal involvement remains an important cause of morbidity and mortality in scleroderma. The objective of this review is to describe the renal complications of scleroderma.

Keywords : Systemic sclerosis; Scleroderma renal crisis; Kidney; Renal function.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )