Abstract

VELASQUEZ-FRANCO, Carlos Jaime  and  RODRIGUEZ-CASTRILLON, Juan Camilo. Raynaud's phenomenon, capillaroscopy, and digital ulcers as sentinel events in systemic sclerosis. Rev.Colomb.Reumatol. [online]. 2020, vol.27, suppl.1, pp.170-174.  Epub Aug 21, 2021. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.07.011.

Raynaud's phenomenon is a sentinel event in systemic sclerosis; it is generally long- lasting, and repeated attacks produce, ultimately, structural consequences and complications, such as digital ulcers. Nailfold videocapillaroscopy is a non-invasive tool that allows assessing accurately these changes. Digital ulcers are the most aggressive and frequent microvascular complication in this disease, causing severe pain and significant functional sequelae. This literature review focuses on Raynaud's phenomenon as a central event in systemic sclerosis, its peculiarities in this entity, the role of capillaroscopy as a biomarker in this vasculopathic phenomenon, as well as a on a clinical and pharmacological approach to digital ulcers in this illness.

Keywords : Scleroderma; Systemic Raynaud disease; Ulcer.

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