Abstract

FRADE-SOSA, Beatriz et al. Diagnosis and treatment of articular manifestations of systemic lupus erythematosus. Rev.Colomb.Reumatol. [online]. 2021, vol.28, suppl.1, pp.90-100.  Epub Feb 18, 2022. ISSN 0121-8123.

Articular involvement in Systemic Lupus Erythematosus (SLE) is well recognized as one of the most common manifestations of the disease. This article reviews the recent knowledge of the clinical manifestations, diagnostic techniques and therapies used for the treatment of joint involvement in SLE. The degree of articular involvement is characterized by widespread heterogeneity in terms of clinical presentation and severity. It may range from minor arthralgia without erosions or deformity to erosive arthropathy and severe functional disability. Inflammatory musculoskeletal manifestations are described as a major cause of pain impacting daily activities and as a major determinant of quality-of-life impairment. Thus, physicians must be aware of articular involvement in SLE. Lupus arthritis diagnosis may be challenging, due to the frequently mild synovitis. The introduction of new more sensitive imaging techniques, such as ultrasound, and MRI have contributed significantly to improving the diagnosis of osteoarticular involvement in SLE. There are several treatment options for the management of joint manifestations in patients with SLE. The choice of treatment will depend on the type and pattern of joint involvement, its severity, and the characteristics of the patient.

Keywords : Systemic Lupus Erythematosus; Arthritis; Arthralgia; Synovitis; Magnetic resonance imaging; Ultrasonography.

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