Abstract

BUITRAGO, Andrés F; SILVA, Luis E; PRADA, Leidy P  and  LOBATO, Libardo. Pericardial effusion secondary to tyrosine kinase inhibitor with imminence of cardiac tamponade: case report. Rev. Colom. Cardiol. [online]. 2011, vol.18, n.2, pp.119-123. ISSN 0120-5633.

Leukemia is a malignant disease characterized by uncontrolled proliferation of a clone initiated at an early stage of lymphoid differentiation. It is important to determine if there is a genetic disorder known as the Philadelphia chromosome, for both prognosis and treatment. Imatinib, a tyrosine kinase inhibitor has good therapeutic response and few adverse effects. An adverse event is the frequent occurrence of serositis manifested as pleural effusion, but its association with pericardial effusion has a lower incidence. Treatment should be individualized, but in case of imminent cardiac tamponade pericardiocentesis is performed.

Keywords : imatinib; tyrosine kinase inhibitors; pericardial effusion.

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