Abstract

GARCIA-CARDONA, Diana M; A. NIETO, Olga  and  LANDAZURI, Patricia. Effect of exercise in HDL subpopulations, lecithin-cholesterol acyltransferase enzyme (LCAT) and ester transfer proteincholesterol (CETP) in medical students. Rev. Colomb. Cardiol. [online]. 2015, vol.22, n.6, pp.277-284. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2015.04.007.

Objective: To evaluate exercise effect on HDL subpopulations, lecithin-cholesterol acyltransferase enzyme and ester transfer protein cholesterol levels in medical students. Method: Population was divided voluntarily into 2 groups, exercise and no exercise. Waist circumference and body mass index were measured; subfractions HDL₂ and HDL₃ by ion precipitation and LCAT and CETP enzymes Enzyme-Linked Immuno-Sorbent Assay (ELISA). Results: Lipidrisk profile increased in both groups; HDL, HDL₂ and HDL₃ decreased in both groups, but only the HDL₂ decreased significantly in students who exercised. LCAT and CETP remained without significant changes, however, in the exercise group, there was statistically significant decrease in HDL₂ and LCAT in women. Conclusions: This study shows that exercise does alter some variables such as waist circumference, body mass index and HDL₃. These changes are dependent on gender, but despite the intervention of 3 months with an exercise program, it fails reducing lipid risk factors in this medical student populations, given their environment, which complicates their metabolic response to exercise.

Keywords : Exercise; Enzymes; High density lipoproteins cholesterol; Medicine students.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )