Abstract

RODRIGUEZ-GONZALEZ, María Juliana; WADNIPAR-GUTIERREZ, Malka Irina  and  CALVO-BETANCOURT, Lauren Sofía. Eosinophilic myocarditis as a cause of reversible left ventricular dysfunction. Rev. Colomb. Cardiol. [online]. 2017, vol.24, n.1, pp.56-56. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2016.01.020.

Eosinophilic myocarditis is a little-known entity as its histopathological diagnosis is conducted in the most severe cases, where an endomyocardial biopsy is mandatory. However, because this condition is usually overlaps with many pathologies -infectious, immunological, or associated to hypersensitivity, and this is related to reversibility- it is important to keep it in mind as a nosological entity in acute presentations of left ventricular dysfunction.

It may or may not be associated to peripheral eosinophilia, though its absence does not rule out the condition. A case of a young male patient (35 year-old) with clinical features of acute cardiac failure which progresses rapidly into cardiogenic shock with low response to initial management (inodilators, vasopressors) requiring the use of extracorporeal circulation support is presented. Previous history: recent completion of treatment for ucocutaneous leishmaniases with meglumine antimoniate (glucantime). Pathology service report: eosinophilic yocarditis.

Weaning from circulatory support is achieved, presenting an improvement of systolic function of the left ventricle with complete recovery of the symptomatology. This case is relevant due to the diagnosis of acute ventricular dysfunction with an association with meglumine antimoniate (glucantime) that was previously not described. It reminds of the importance of carrying out an endomyocardial biopsy in order to define the aetiology and the decision-making on advances therapies, knowing that in some circumstances there can be a reversibility of the myocardial function and an improvement of the symptomatology.

Keywords : Myocarditis; Acute heart failure; Heart failure; Cardiac assist device;.

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