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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
RUALES-MORA, Kevin Y. et al. Sociodemographic, clinical and therapeutic characteristics of patients with heart failure with mid-range ejection fraction: MED-ICAi cohort. Rev. Colomb. Cardiol. [online]. 2021, vol.28, n.3, pp.254-262. Epub July 29, 2021. ISSN 0120-5633. https://doi.org/10.24875/rccar.m21000050.
Background:
Classically, heart failure has been classified in two groups, depending on a preserved or reduced ejection fraction, but a mid-range ejection fraction group has been introduced recently, and there is still great ignorance about its physiopathological and clinical characteristics.
Objective:
To characterize this group of patients as for their sociodemographic, clinical and treatment variables.
Method:
We carried out a descriptive, retrospective study, by analyzing medical records from patients hospitalized with acute heart failure between January 2015 and December 2017.
Results:
We reviewed 1536 medical records of which 864 met the inclusion criteria. The mid-range ejection fraction group corresponded to 83 (9.6%) of patients, of which the majority were women (53%), with a median age of 77 years, coronary heart disease as the most frequent etiology (26.5%) and lack of adherence to medications as the main cause of decompensation (14.5%). The most frequently used drugs were betablockers and furosemide, both upon admission and discharge. Mortality was higher between patients with reduced ejection fraction (4.1%). Hospital stay, admission to and length of stay in an ICU, were similar between all groups regardless of ejection fraction.
Conclusions:
Our findings are similar to those described in previous international and national cohorts, and support the hypothesis of an intermediate phenotype with an etiology similar to that seen with a reduced ejection fraction.
Keywords : Heart failure; Stroke volume; Mortality; Risk factors.