Abstract

ORREGO-CARDOZO, Mary et al. Porphyromonas gingivalis and systemic diseases. CES odontol. [online]. 2015, vol.28, n.1, pp.57-73. ISSN 0120-971X.

Abstract Porphyromonas gingivalis (P.g.) is a gram-negative coccobacillus that resides in the gingival sulcus. Some of its structural pathogenic factors like fimbriae allow its adhesion to the tissues of the gingival sulcus, where P.g. secretes proteases and hyaluronidases that hydrolyze components of the periodontal tissues, leading to tissue damage and loss of teeth support. Some bacterial components such as lipopolysaccharides have been associated with systemic diseases. This review focuses on the molecular mechanisms linking the pathogenic factors of Porphyromonas gingivalis to diseases such as atherosclerosis, pulmonary disease and preterm birth

Keywords : Porphyromonas gingivalis; periodontitis; atherosclerosis; preterm birth; pathogenic factors; pulmonary disease.

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