Abstract

BARROS GOMES, Paulo Roberto et al. Chemical characterization and cytotoxicity of clove essential oil (Syzygium aromaticum). Rev. colomb. cienc. quim. farm. [online]. 2018, vol.47, n.1, pp.37-52. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v47n1.70657.

This work evaluates the physical-chemical properties of the essential oil of the dry floral buds of clove (Syzygium aromaticum) that are found in the Municipality of Saint Louis, Maranhão. The essential oil was quantitatively extracted by hydrodistil lation. The physicochemical properties of the essential oil (density, refractive index, solubility, color and appearance) and cytotoxic activity against larvae of Artemia salina were determined. The oil was analytically characterized by gas chromatog raphy coupled to mass spectrometer (GC-MS). The results show that the best time and yield of the oil were correspondingly 4 hours and 4.33% mass per volume. From this, it was possible to identify five components, being the major presence of eugenol that soon was confirmed by the spectroscopic techniques. In the identification of the major component and the other components, as well as their quantifications, the techniques were precise and the methods efficient, providing a good analytical performance in the determinations.

Keywords : Physical-chemical evaluation; Syzygium aromaticum; floral buds; Eugenol; hydrodistillation.

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