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Revista Colombiana de Obstetricia y Ginecología
Print version ISSN 0034-7434On-line version ISSN 2463-0225
Abstract
SALAMANCA U, Andrés. Neonatal screening: risk assessment of aneuploidies. Rev Colomb Obstet Ginecol [online]. 2003, vol.54, n.4, pp.213-226. ISSN 0034-7434.
Prenatal screening of aneuploidies has showed important evolution since the time when the only form of screening was maternal age, up to the present with the use of ultrasound and first trimester serologic markers. The present review emphasizes on the use of nuchal translucency as a first trimester ultrasound marker, its correct application, and the interpretation of results as well as its relationship with other first and second trimester serological markers. The most relevant studies on the subject reveal detection rate that varies depending on the strategy chosen for the prenatal screening process and in accordance with the different false positive rates. Each day new markers and strategies appear. However, they should be thoroughly reviewed before using them in everyday practice.
Keywords : nuchal translucency; risk assessment; aneuploidy; first trimester.