Abstract

MENESES-JACOME, Claudia et al. Is Asthma Severity Related to Generalized Anxiety Disorder and Mayor Depressive Disorder? A Case-Control Study. rev.colomb.psiquiatr. [online]. 2009, vol.38, n.3, pp.464-470. ISSN 0034-7450.

Introduction: World-wide more than one hundred million people suffer from asthma. This population presents a high prevalence of major depressive disorder (MDD) and generalized anxiety disorder (GAD). However, this association has not been investigated IN Colombian asthma outpatients. Objective: To establish whether asthma severity is associated with MDD or GAD in adult asthma outpatients in Bucaramanga, Colombia. Method: A study on cases (44 patients with severe asthma) and controls (88 patients with mild asthma), matched according to age, sex and socioeconomic status, was designed. The current MDD and GAD diagnoses were made using the Structured Clinical Interview for D SM-IV Axis I Disorders-Clinical version (SCID-CV). Results: The current prevalencE of MDD WAS 27.2% and 29.5% in patients with mild asthma and patients with severe asthma, respectively (OR=1.12, 95% CI 0.46- 2.69). The prevalence of GAD was 43.1% and 45.4% in patients with mild asthma and patients with severe asthma, respectively (OR=1.10, 95% CI 0.49-2.44). Conclusion: There is no association between MMD and GAD and the degree of severity in asthma patients in Bucaramanga, Colombia.

Keywords : Major depressive disorder; anxiety disorders; outpatients; asthma; casecontrol studies.

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