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Revista Colombiana de Psiquiatría
Print version ISSN 0034-7450
Abstract
ONATE-CADENA, Nelcy et al. Deep-brain stimulation in treatment-resistant obsessive-compulsive disorder: Clinical and molecular neuroimaging correlation. rev.colomb.psiquiatr. [online]. 2020, vol.49, n.1, pp.62-65. Epub June 12, 2020. ISSN 0034-7450. https://doi.org/10.1016/j.rcp.2018.05.002.
Introduction:
Obsessive-compulsive disorder is defined by the presence of obsessions and compulsions that cause marked anxiety or distress and has been associated with a disruption in corticostriato-thalamo-cortical circuitry. After treatment, around 50% of patients continue to experience incapacitating symptoms. Deep-brain stimulation has been shown to be an effective therapeutic alternative to regular treatment.
Methods:
Case report.
Case presentation:
A 54-year-old woman with a diagnosis of treatment-resistant obsessive-compulsive disorder was treated with deep-brain stimulation of the anterior limb of the internal capsule. Molecular imaging before and after the procedure was obtained and correlated with clinical features.
Conclusions:
Deep-brain stimulation may be a therapeutic alternative to regular care in treatment-resistant obsessive-compulsive disorder and can be correlated to functional changes in suspected anatomical structures.
Keywords : Obsessive-compulsive disorder Deep-brain stimulation Treatment-resistant Molecular imaging.
