Abstract

CAMARGO-MENDOZA, Juan Pablo; RODRIGUEZ-ARIZA, Daniel Efrén  and  BUSTOS-CALVO, Jhonny Steven. Heparin and insulin in the management of acute hypertriglyceridemic pancreatitis. Acta Med Colomb [online]. 2020, vol.45, n.1, pp.44-47.  Epub Sep 15, 2020. ISSN 0120-2448.  https://doi.org/10.36104/amc.2020.1491.

Hypertriglyceridemic pancreatitis (HTGP) is the third cause of acute pancreatitis in most studies, with a triglyceride (TG) risk value of more than 1000 mg/dL. The pathophysiological mechanism involves triglyceride hydrolysis by pancreatic lipase and the release of fatty acids which cause damage by producing free radicals. The reduction of TGs below 500 mg/dL is the treatment goal, based on increased lipoprotein lipase activity and chylomicron degradation. We present the case of a patient with HTGP with an adequate response to concomitant insulin and heparin therapy. (Acta Med Colomb 2020; 45. DOI: https://doi.org/10.36104/amc.2020.1491).

Keywords : acute pancreatitis; heparin; insulin; lipoprotein lipase.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )