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Biomédica
Print version ISSN 0120-4157On-line version ISSN 2590-7379
Abstract
JOYA, Milagros; HEREDIA, Ricardo; BASTIDAS, Daniel and BASTIDAS, Gilberto. Detection of Chlamydia trachomatis infection in sexually active women in Venezuela. Biomed. [online]. 2022, vol.42, n.3, pp.522-530. Epub Sep 02, 2022. ISSN 0120-4157. https://doi.org/10.7705/biomedica.6246.
Introduction:
Genital Chlamydia trachomatis infection is one of the most frequent in the world; about 85 million new cases of this pathology are registered each year, which causes severe complications in women and newborns.
Objective:
To determine the clinical-epidemiological characteristics of C. trachomatis infection in sexually active Venezuelan women.
Materials and methods:
Descriptive, cross-sectional, and field study based on the clinical history and physical examination, detection of infection with immunoenzymatic assay with anti-LPS polyclonal antibody and confirmation of results with molecular biology test. The sample consisted of 100 sexually active women over 12 years of age from Carabobo state, Venezuela.
Results:
The women were mostly between 20 and 45 years old, in 25% of them IgG antibodies to C. trachomatis were detected and in 84% of these the infection was confirmed by PCR, in none of the women IgM antibodies to C. trachomatis were found.
Conclusion:
Chronic infection characterizes women between 20 and 45 years of age; the immunoenzymatic test yielded false positives corroborated by PCR.
Keywords : Chlamydia trachomatis; infection; immunoglobulin M; immunoglobulin G; chain reaction polymerase; epidemiology.