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Revista Salud Uninorte
Print version ISSN 0120-5552On-line version ISSN 2011-7531
Abstract
PINO ASTORGA, Carolina; ROCO VIDELA, Ángel and VALLADARES VEGA, Macarena. Potential Joint Effect of the SNP rs3749474T and SNP rs4864548AAlleles of the CLOCK Gene on Nutritional Status and Chronotype in Young University Students. Salud, Barranquilla [online]. 2021, vol.37, n.1, pp.11-20. Epub Feb 28, 2022. ISSN 0120-5552. https://doi.org/10.14482/sun.37.1.613.2.
Objective:
To compare the nutritional status, chronotype and eating behavior of a subject who simultaneously has the rs3749474T and rs4864548A polymorphisms to groups of subjects who have only one of these polymorphisms.
Methods:
The presence of the polymorphisms was established by PCR. BMI, cardiovascular risk, and fat percentage were determined as described by Durnin and Womersley and the Siri equation. The TFEQ-P19 questionnaire (adapted to the Chilean population) and the Hor-ne-Ostberg questionnaire were applied.
Results:
The subject with both polymorphisms presented obesity, cardiovascular risk, and late-night chronotype. Its scores on the dimensions of uncontrolled feeding and emotional feeding were low, and its score for cognitive restriction was the highest.
Conclusions:
The presence of the TA haplotype (rs3749474; rs4864548A) would increase the possibility of having a late-night type chronotype, risk of obesity, and cardiovascular risk associated with waist centimeters.
Keywords : CLOCK gene; obesity; chronotype.
