Abstract

SIMANCAS-ESCORCIA, Víctor; MARTINEZ-VARGAS, Jesús; PACHECO-RAMIREZ, Maryi  and  DIAZ-CABALLERO, Antonio. Gingival overgrowth induced by orthodontic treatment: histological and immunohistochemical analysis of two clinical cases. Salud, Barranquilla [online]. 2023, vol.39, n.1, pp.319-326.  Epub Nov 20, 2023. ISSN 0120-5552.  https://doi.org/10.14482/sun.39.01.247.822.

Orthodontic treatment-induce gingival overgrowth (OTGO) is uncontrolled growth of the gingiva. Here, we report two clinical cases of systemically healthy male patients with generalized GH undergoing orthodontic treatment, with and without association with dental biofilm. In both patients, hyperplastic epithelial tissue was identified with abundant Ki-67 positive cells and connective tissue rich in randomly distributed collagen fibers. Future studies will be useful to elucidate the pathophysiological differences of OTGO with and without relation to dental biofilm.

Keywords : orthodontics; gingival overgrowth; Ki-67 antigen; cell Proliferation; collagen.

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