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Acta Neurológica Colombiana

Print version ISSN 0120-8748On-line version ISSN 2422-4022

Abstract

MARTINEZ-VILLOTA, Viviana Alexandra  and  PORTILLO MINO, José Dario. Thrombolysis for ischemic stroke in a reference hospital in Nariño - Colombia. Acta Neurol Colomb. [online]. 2021, vol.37, n.4, pp.189-196.  Epub Dec 03, 2021. ISSN 0120-8748.  https://doi.org/10.22379/24224022387.

INTRODUCTION:

Stroke is the second leading cause of death and third of disability in the world. Intravenous Thrombolysis as a treatment for acute ischemic stroke has been shown to reduce disability and mortality; however, it is directly linked to administration time and adequate stroke care attention. Through this work, the times of attention in thrombolysis are evaluated at the Hospital Universitario Departamental de Narino E.S.E, as a local reference institution in Colombia.

METHODS:

A retrospective descriptive study included patients with ischemic stroke who received intravenous thrombolysis between 2014 and 2019. The analysis was performed using descriptive statistics and absolute and relative frequencies. To assess the differences, it was divided into three attention periods.

RESULTS:

50 patients were evaluated, with an average age of 67.6 years, 58% men. In 70% a decrease greater than 3 NIHSS points was observed post-thrombolysis. The 58% had mRS 0-1. There was a difference between the medians in the Door-CT time with 36.5 (n = 10, 2014-2015), 34.5 (n = 16, 2016-2017) and 16 minutes (n = 24, 2018-2019). And in the Door-Needle time was 154.8; 98.2 and 79.9 minutes in the same periods. In 45.8%, the Door-Needle time was less than 60 minutes in the third period.

CONCLUSIONS:

There is evidence of an increase in the number of patients receiving intravenous thrombolysis throughout the years evaluated, as well as a decrease in Door-CT and Door-Needle times, as markers of improvement in clinical care.

Keywords : Stroke; Thrombolytic Therapy; Developing Countries; Tissue Plasminogen Activator; Quality of Health Care; Quality Indicators, Health Care.(MeSH).

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