Services on Demand
Journal
Article
Indicators
Cited by SciELO
Access statistics
Related links
Cited by Google
Similars in SciELO
Similars in Google
Share
Revista colombiana de Gastroenterología
Print version ISSN 0120-9957On-line version ISSN 2500-7440
Abstract
BEJARANO CASTRO, Mónica and MENDEZ PAZ, Fabián. Interaction of factors associated to an ulcer-pelvic disease. Rev Col Gastroenterol [online]. 2006, vol.21, n.1, pp.25-32. ISSN 0120-9957.
Previous publications described that peptic ulcer disease is associated with Helicobacter pylori infection and non-steroidal anti-inflammatory drugs intake. However, many aspects of peptic ulcer disease ethiopatogenesis are still unknown. A hospital-based case-control study was carried out based on 1,157 individuals who consulted at a general practice clinic in Cali, Colombia, because of gastrointestinal symptoms. Cases were individuals with endoscopic diagnosis of ulcer (n=161) while controls had diagnosis of non-ulcer dyspepsia (n=996). Factors positively associated with peptic ulcer were H. pylori infection (OR:3.28) and NSAID intake (OR:1.75), besides age (>70 years OR:1.95), male sex (OR:2.99), peptic ulcer history (OR:4.65), smoking habits (OR:2.49), alcohol consumption (OR:1.74) and anticoagulants (OR:3.88). Our study suggests that the association between NSAID and peptic ulcer is modified by male sex and alcohol consumption.
Keywords : Peptic ulcer; Non-ulcer dispepsia; Helicobacter pylori; Non-steroidal anti-inflammatory drugs (NSAID); Interaction.