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Revista colombiana de Gastroenterología
Print version ISSN 0120-9957On-line version ISSN 2500-7440
Abstract
MARTINEZ-MONTALVO, Carlos Mauricio et al. Cardiac hemodynamic variables and post-liver transplant outcomes in a transplant referral center in Colombia at 2,600 meters above sea level. Rev. colomb. Gastroenterol. [online]. 2022, vol.37, n.4, pp.390-400. Epub July 07, 2023. ISSN 0120-9957. https://doi.org/10.22516/25007440.923.
Introduction:
Hemodynamic assessment by Doppler echocardiography is essential in identifying systolic/diastolic changes as a predictor of outcomes in post-liver transplantation, from cardiovascular changes to graft dysfunction and mortality.
Materials and methods:
Retrospective cohort study. Patient with a liver transplant at the LaCardio hospital in Bogotá, Colombia, between January 2005 and July 2021. Analysis of sociodemographic variables, comorbidities, echocardiography, and intraoperative variables with primary outcomes such as early graft dysfunction, acute kidney injury (AKI), and mortality during follow-up. A classification and regression tree (CART) was performed.
Results:
397 patients were analyzed; 54.4% were men, 71% had some degree of diastolic dysfunction and left ventricular hypertrophy (30.9%) with graft dysfunction in 8% and AKI in 21%, and a mortality of 15% during the study follow-up. In the CART model, mortality and graft dysfunction outcomes were related to a body mass index (BMI) < 19 or a combination of BMI between 19 and < 24 with dialysis.
Conclusion:
Echocardiographic variables, sarcopenia, AKI, or the requirement for renal replacement therapy are related to mortality and graft dysfunction outcomes.
Keywords : Liver transplantation; liver cirrhosis; ventricular dysfunction.
