Abstract

BRETON-GOMEZ, Guillermo Andrés et al. Paget’s disease of the breast: review of the literature. Medicas UIS [online]. 2021, vol.34, n.1, pp.45-53.  Epub Apr 01, 2021. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v34n1-2021005.

Paget’s disease of the breast is an uncommon neoplasm of the breast, many times difficult to diagnose and of poor prognosis. The objective is to review the fundamental clinical and diagnostic aspects, as well as the most recent advances in its treatment. A bibliographic search of the last 20 years was carried out through PUBMED, GOOGLE SCHOLAR and UPTODATE. 38 articles were selected and included in the review. Mammary paget disease is a rare malignant neoplasm of the nipple areola complex with inflammatory features on physical examination, associated in 85% of cases with underlying breast cancer, in 50% of cases not recognizable on physical exam, difficult to diagnose, whose clinical suspicion is confirmed by imaging, biopsy and immunohistochemistry. Treatment is mastectomy versus conservative surgery and radiotherapy. A poor clinical approach delays the diagnosis and worsens survival rate. MÉD.UIS.2021;34(1): 45-53.

Keywords : Mammary Paget’s Disease; Segmental Mastectomy; Breast Neoplasms.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )