Abstract

RINCON-RIANO, Diana Nathalie; FERNANDEZ-AVILA, Daniel G.  and  GUTIERREZ, Juan M.. Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus. Rev.Colomb.Reumatol. [online]. 2017, vol.24, n.4, pp.242-246. ISSN 0121-8123.

Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

Keywords : Leflunomide; Stevens-Johnson syndrome; Adverse effects.

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