Abstract

VELASQUEZ, María del Pilar Montilla; MORENO, Germán Camacho; ROMERO, Sandra Liliana  and  GOMEZ, Karen. Risk factors associated with complications of Bordetella pertussis at the Fundacion Hospital de la Misericordia, 2009-2013 . Infect. [online]. 2015, vol.19, n.3, pp.101-108. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2015.02.002.

Objective: To characterize the risk factors associated with complications in patients infected with Bordetella pertussis , 2009-2013. Material and methods: Case-control study. Identification of risk factors associated with complications in patients with Bordetella pertussis , confirmed by polymerase chain reaction. Results: A total of 96 patients were characterized. 76% were younger than 6 months, mean 4.56 ± 6.8 months; there were 58.3% boys and 41.5% girls. A total of 51% had complications. Some 58% were hospitalized in critical care. Sepsis occurred in 9.4% patients, and 14.6% required assisted ventilation. A total of 4.2% died. The mean critical care stay was 8.75 days ( ± 85) and the mean hospital stay was 13.92 ± 12.81 days. The following risk factors associated with complications were identified: notion of contagion (OR: 2.20), no vaccination (OR: 3.31). Clinical: (OR: 4.07) cyanosis, dehydration (OR: 2.72), tachycardia (OR: 2.64), tachypnea (OR: 3.94), desaturation (OR: 3.34). Paraclinical: Bacterial co-infection (OR: 7.66), lymphocytosis (OR: 3.18), thrombocytosis (OR: 3.038). Conclusion: Background, clinical and paraclinical factors can identify patients with B. pertussis infection at risk for complications and admission to the critical care unit.

Keywords : Whooping cough; Risk factors; Complications; Polymerase chain Reaction.

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