Abstract

PEREZ CARDENAS, Jorge Enrique; SEPULVEDA-ARIAS, Juan Carlos; ACOSTA AGUDELO, Sandra Milena  and  ISAZA MEJIA, Gustavo. EFFECT OF AQUEOUS AND METHANOLIC EXTRACTS OF PHENAX RUGOSUS (POIR.) WEDD. AND TABEBUIA CHRYSANTHA G. NICHOLSON, ON THE PRODUCTION OF IgG_2b AND IgM ANTIBODIES IN RATS. A PRELIMINARY STUDY. Biosalud [online]. 2009, vol.8, n.1, pp.37-46. ISSN 1657-9550.

Previous Ethnopharmacological studies have showed the use of Phenax rugosus (Poir.) Wedd. and Tabebuia chrysantha G. Nicholson leaves for the treatment of infectious diseases and in inflammatory processes. Aqueous and methanolic extracts of each plant was obtained in order to determine the capacity of these extracts to induce significant changes in the seric levels of IgM and IgG_2b antibodies in Wistar rats. The results obtained show that these extracts do not produce a response with statistical significance when comparing the antibody levels between the control and treatments groups.

Keywords : Tabebuia chrysantha; Phenax rugosus; antibodies; IgM; IgG2b; natural products.

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