Introduction:

The gaps between health research and its practical application constitute an object of study and a field of intervention in the health sphere. The translation and use of research-based knowledge are considered crucial to improve public health and health systems.

Development:

The aim of this paper is to review and compare the conceptual approaches translational research, knowledge translation, and knowledge mobilization. These approaches have been theoretically and institutionally developed in countries with strong health research systems such as the United States, Canada, and the United Kingdom, while in Latin America, they have not been sufficiently studied. To analyze the knowledge transfer processes conception and their main contributions and limitations. The knowledge mobilization approach stands out as a wider framework, which includes the social nature of the production, transfer, and use of knowledge.

Conclusions:

The knowledge mobilization approach is a suitable framework for studying and systematizing experiences on the use of health knowledge in Latin America, aiming at strengthening National Health Research Systems.

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