Abstract

BOHORQUEZ RIVERO, José et al. Hemodialysis-Associated Amyloidosis: Review of its ethiopathogenic aspects. Rev. colom. nefrol. [online]. 2021, vol.8, n.2, e302.  Epub Jan 01, 2022. ISSN 2500-5006.  https://doi.org/10.22265/acnef.8.2.511.

Amyloidosis is a major complication in patients with chronic kidney disease who undergo hemodialysis for long periods of time. As in other systemic amyloidosis, different substances are involved in amyloidosis associated with different substances, some of them fibrillar in nature, such as βeta-2-microglobulin, which represents one of the most relevant proteins given its etiopathogenic involvement. Despite the fact that hemodialysis techniques have been improved over the years, this entity continues to be a frequent complication; such is that it can occur in up to 80% of patients with prolonged hemodialysis. Therefore, it was essential to carry out a narrative review based on the scientific literature available in the different databases with the aim of contributing to improve and update the doctor's knowledge on this topic; ranging from the general aspects and its pathophysiology, to its clinical presentation, diagnosis, and treatment.

Keywords : Amyloidosis; Chronic Kidney Disease; Renal Dialysis; Complications; βeta-2-Microglobulin; joint..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )