Abstract

GUERRERO VARTICOVSKY, Ana Valeria; BENITEZ CARDOZA, María Clara; POLO CASTILLO, Ariel  and  BOLANO CERVANTES, Marco. Congenital nephrotic syndrome debuting with disease of minimal changes. Rev. colom. nefrol. [online]. 2021, vol.8, n.2, e705.  Epub Jan 01, 2022. ISSN 2500-5006.  https://doi.org/10.22265/acnef.8.2.455.

Nephrotic syndrome is the most common primary glomerulopathy in pediatrics; it is a pathology characterized by the presence of proteinuria, hypoalbuminemia, edema, and hypercholesterolemia. There is talk of a neonate with a history of prematurity and hospitalization at birth, after multiple infections recurrent with torpid evolution during hospital stay and edema generalized, suspected of having congenital nephrotic syndrome, relying on positive paraclinical results and a renal biopsy that reports minimal change disease.

Congenital nephrotic syndrome is a rare entity; However, presents high morbidity and mortality, as well as various forms of clinical and histological, and its management is usually difficult given the low response to corticosteroids. The presence of congenital nephrotic syndrome is unusual; however, it presents high mortality and leaves many sequelae, with chronic kidney disease being the most feared. So, it is important to suspect in newborns with infections recurrent associated with the presence of generalized edema to initiate management early that can help prevent consequences and improve the quality of life of the patient and his family. .

Keywords : congenital nephrotic syndrome; hypoalbuminemia; minimal change disease; edema; proteinuria..

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