Abstract

PEDROZA PALLARES, Álvaro; CASTIGLIONI, Teresa  and  BOUZA, Gabriel. Sclerodermic renal crisis. Rev. colom. nefrol. [online]. 2022, vol.9, n.1, 402.  Epub Jan 01, 2022. ISSN 2500-5006.  https://doi.org/10.22265/acnef.9.1.526.

Systemic sclerosis (SS) is characterized by the presence of thickening and hardening of the skin (from the Greek "sclero"), it has forms of limited and diffuse manifestation. It is chronic in pattern and manifests with vascular dysfunction and severe systemic connective fibrosis. Sclerodermic renal crisis (CRE) is the severe manifestation in the kidney, and is characterized by: a) Malignant hypertension, of sudden onset associated with increased plasma renin activity. There is a clinical variant, which presents with normotension, which has a worse prognosis. (UTAH); b) Acute Renal Failure (ARF); c) Proteinuria in the non-nephrotic range. Microscopic hematuria and casts are uncommon.

Next, we are going to report the presentation of a case of sclerodermic renal crisis (CRE), in a 60-year-old female patient, who was admitted to our institution with a condition characterized by severe arterial hypertension, severe glomerular filtration drop, microhematuria and proteinuria; which received medical treatment, but due to the persistence of signs and symptoms, it was decided to perform a renal biopsy puncture, which confirmed the diagnosis.

Keywords : Acute renal failure; systemic sclerosis; angiotensin converting enzyme inhibitors; hypertension..

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