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Revista Colombiana de Ciencias Químico - Farmacéuticas
versión impresa ISSN 0034-7418
Resumen
BONILLA, Diego M et al. Effect of essential oil of Rosmarinus officinalis on Porphyromonas gingivalis cultivated in vitro. Rev. colomb. cienc. quim. farm. [online]. 2016, vol.45, n.2, pp.275-287. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v45n2.59942.
The interest in natural products as a source of antimicrobial agents has been increasing. Previous studies have shown that plant extract may inhibit bacterial growth in the oral cavity. The aim of this study was to determine the in vitro susceptibility of Porphyromonas gingivalis ATCC 33277 against the essential oil of Rosmarinus officinalis. To evaluate the antimicrobial activity of the essential oil, quantitative agar dilution method described by the Clinical and Laboratory Standards Institute (CLSI) for anaerobic bacteria was used. The essential oil of R. officinalis showed a minimum inhibitory concentration (MIC) of 1000 µg/ml against Porphyromonas gingivalis ATCC 33277. These results suggest that essential oil of R. officinalis may be useful as an antibacterial agent in oral preparations.
Palabras clave : Rosmarinus officinalis; essential oil; Porphyromonas gingivalis.