Resumo

NAVARRO-CARBONELL, Doris Elena; PULIDO-TORRES, Carlos; SAA-MADRINAN, Ángela María  e  LUCENA-QUEVEDO, Elkin. Comparing embryo quality between in vitro fertilization (IVF) and intravaginal ovocyte culture (INVO) in the Colombian Centre for Fertility and Sterility - CECOLFES, Bogotá, Colombia. Rev Colomb Obstet Ginecol [online]. 2012, vol.63, n.3, pp.227-233. ISSN 0034-7434.

Objective: Comparing embryo quality and describing implantation, pregnancy and abortion rates regarding in vitro fertilization (IVF) and intravaginal oocyte culture (INVO) techniques. Materials and methods: The study involved historical cohorts of patients undergoing IVF and INVO treatment in the Colombian Fertility and Sterility Centre (Centro Colombiano de Fertilidad y Esterilidad – Cecolfes) during 2010. It involved 137 aspirated patients, covering four study groups: Group 1 IVF/incubator, Group 2 IVF/INVO, Group 3 ICSI/INVO and Group 4 ICSI/incubator. The patients’ weight, the number of ovocytes retrieved, mature ovules (M2), implantation rate, pregnancy and abortion rates were measured in each group. The Kruskal-Wallis test was used for statistical analysis; embryo quality was evaluated by multivariate covariance analysis (MANOVA). Results: A significant difference was observed regarding embryo quality between IVF and INVO (p = 0.0388), the INVO technique having higher embryo cleavage rates (µ = 7.35/INVO cf 6.64/ incubator) and lower embryo fragmentation (µ = 4.67/INVO cf 4.59/incubator). INVO groups also had higher percentages concerning their implantation, pregnancy and abortion rates. Conclusion: The INVO technique led to obtaining better quality embryos; implantation, pregnancy and abortion rates were similar to those described for the IVF technique.

Palavras-chave : Intravaginal oocyte culture (INVO); in vitro fertilization (IVF); cumulus-corona oocyte complex (CCOC); metaphase II (MII).

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