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Acta Neurológica Colombiana
versão impressa ISSN 0120-8748versão On-line ISSN 2422-4022
Resumo
SIERRA, Valentina et al. Statin treatment and low density cholesterol targets in patients post stroke. Acta Neurol Colomb. [online]. 2022, vol.38, n.4, pp.240-248. Epub 02-Fev-2023. ISSN 0120-8748. https://doi.org/10.22379/24224022433.
INTRODUCTION:
Stroke is one of the most prevalent cardiovascular events in the world, in Colombia it is the second cause of death and first in disability. One of the most important risk factors to consider is cholesterol control, the reduction of LDL-C and cholesterol levels, mainly through treatment with statins and other lipid-lowering drugs.
MATERIALS AND METHODS:
The most relevant information on the use and benefits of this treatment and some additional considerations have been collected in this narrative review of the literature.
CONCLUSION:
The results of this narrative review show the protective effect of this therapy when it is possible to reduce LDL-C and cholesterol levels, in addition to other therapies such as ezetimibe or PSCK9 inhibitors. On the other hand, studies mention possible beneficial effects in the context of stroke but more clinical trials are required.
Palavras-chave : Cholesterol, LDL; Hydroxymethylglutaryl-CoA reductase inhibitors; Hypolipidemic agents; Stroke (MeSH).