Resumo

MUNOZ-ORTIZ, Edison; AREVALO-GUERRERO, Edwin; ABAD, Pedro  e  SENIOR, Juan Manuel. Cardiac sarcoidosis. State of the art. Iatreia [online]. 2016, vol.29, n.4, pp.458-469. ISSN 0121-0793.  https://doi.org/10.17533/udea.iatreia.v29n4a07.

Sarcoidosis is a rare disease of unknown etiology, described over 80 years ago. It is a multisystemic disorder characterized by the presence of granulomatous lesions without caseation. Cardiac involvement varies according to the region, but it is generally accepted that 5 % of patients with systemic sarcoidosis have cardiac infiltration with clinical evidence; however, autopsy studies indicate that up to 20 % to 30 % of patients with sarcoidosis have myocardial involvement. Several factors -environmental, occupational and infectious- have been proposed as triggers of the process in individuals with genetic predisposition. Cardiac sarcoidosis may have a wide range of presentations and may even be asymptomatic; the most common manifestations are heart failure, abnormal heart rhythm and lethal ventricular arrhythmias. Treatment includes medications for heart failure, steroids and immune-suppressants, management of lethal arrhythmias with ablation and/ or implantable cardioverter defibrillator and cardiac transplantation in severe cases.

Palavras-chave : Arrhythmias; Heart Failure; Sarcoidosis.

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