Resumo

CURIEL, Julio; OLAYA ORDONEZ, Martin Alonso; ORTIZ FONSECA, Wilman Orlando  e  LOZANO DIAZ, Manuel Leonardo. Neuronal migration disorders: a lissencephaly case. Revista médica Risaralda [online]. 2014, vol.20, n.2, pp.129-132. ISSN 0122-0667.

Malformations of cortical development originate a group of pathologies that involve diverse manifestations that mark a significant degree of disability in those who suffer from. The Lissencephaly is one of alterations in neuronal migration characterized by a smooth surface or with few convolutions in the cerebral cortex. This disorder is often associated with difficult management Epilepsies. We report the case of a male patient from 18 months of age with a diagnosis of Lissencephaly, who presents generalized tonic seizures from 8 months of age. Was performed a simple skull CT and brain magnetic resonance to confirm the diagnosis and the pharmacological management was given to seizures

Palavras-chave : lissencephaly; malformations of cortical development; pachygyria; epilepsy.

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