Background:

There are energy and nutrient recommendations for a healthy population; however, important functions in different health situations are attributed to nutrients such as vitamins D, E, K, E and K.

Objective:

To explore the effectiveness of dietary doses and supplements of vitamins D, E and K in special conditions of health and disease.

Materials and Methods:

A document search was carried out in the PubMed, Scopus, Sciencedirect, Lilacs, Scielo and Ebsco databases, and in specialized texts using keywords: “vitamin D”, “vitamin E”, “vitamin K”, “Health”, “disease”, “nutritional recommendations”.

Results:

There is a significant number of studies and systematic reviews that contribute to the evidence and discussion regarding effect, dose and time, which yielded both positive and null outcomes.

Conclusion:

The effects of dietary vitamin D in bone health are well documented and its supplementation accompanied by calcium is indicated in population groups at risk for osteoporosis, but not in other clinical conditions. There is insufficient evidence on the benefits of vitamin E in the management or prevention of liver disease, cardiovascular disease, or cancer. Vitamin K could be important in bone health, over other clinical conditions.

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