Resumo

LEON A., LAURA ANDREA et al. Corticosterone plasma concentrations in Carioca High-and Low-conditioned freezing rats after a fear conditioned task. Av. Psicol. Latinoam. [online]. 2013, vol.31, n.1, pp.279-287. ISSN 1794-4724.

Our group in the Psychology Department at Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio) developed a rat genetic model of extreme freezing in response to contextual cues in an experimental chamber previously associated with footshock. One of the lines, Carioca High Freezing (CHF), exhibits an enhanced conditioned freezing response, whereas the other line, Carioca Low Freezing (CLF), shows the opposite response. The present study investigated corticosterone concentration between these two lines of animals and a random (RND) line of rats both under basal conditions and test condition after an emotional challenge using a contextual fear conditioning protocol. Comparisons between basal and test plasma corticosterone concentrations suggested differential basal and fear-induced differences between the two lines. The differences between basal conditions is an important and relevant aspect to be considered in behavioral experiments using or assessing stress and could help to understand variability in naïve populations.

Palavras-chave : anxiety traits; corticosterone; fear; rats.

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