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Revista Colombiana de Nefrología
versão On-line ISSN 2500-5006
Resumo
AROCHA-RODULFO, José Ildefonzo e MAINI, Pablo Amair. Metformin in kidney diabetic disease: Current state. Rev. colom. nefrol. [online]. 2017, vol.4, n.2, pp.188-199. ISSN 2500-5006. https://doi.org/10.22265/acnef.4.2.255.
Current therapy directed at delaying the progression of diabetic renal disease includes intensive glycemic and optimal blood pressure control, renin angiotensin-aldosterone system blockade and multifactorial intervention. However, the renal protection provided by these therapeutic modalities is not complete. There is a scarcity of studies analyzing the nephroprotective effect of antihyperglycemic drugs beyond their glucose lowering effect and progression of diabetic renal disease. This article updates the existing data about metformin in diabetic kidney disease.
Palavras-chave : Diabetic renal disease; metformin; antihyperglycemic; nephroprotective.