Resumo

PEDROZA PALLARES, Álvaro; CASTIGLIONI, Teresa  e  BOUZA, Gabriel. Sclerodermal kidney crisis. Rev. colom. nefrol. [online]. 2021, vol.8, n.2, e703.  Epub 01-Jan-2022. ISSN 2500-5006.  https://doi.org/10.22265/acnef.8.2.516.

Systemic sclerosis (SS) is characterized by the thickening and hardening of the skin (from the Greek "sclero"); it has forms of limited and diffuse manifestation. It is chronic in pattern and manifests as vascular dysfunction and severe systemic connective fibrosis. Scleroderma renal crisis (CRE) is a severe manifestation in the kidney characterized by malignant hypertension of sudden onset associated with increased plasma renin activity. There is a clinical variant with normotension which has a worse prognosis called Acute Renal Failure (ARF), and thrombotic microangiopathy. Microscopic hematuria and casts are uncommon.

We report a case of scleroderma renal crisis (CRE) in a 60-year-old female patient who entered the Sanatorio de los Arcos in Buenos Aires, Capital Federal (Argentina) with severe arterial hypertension, severe glomerular filtration drop, microhematuria and proteinuria. She received medical treatment; nevertheless, it was decided to perform a renal biopsy puncture due to the persistence of signs and symptoms, which confirmed the diagnosis.

Palavras-chave : acute renal failure; systemic sclerosis; angiotensin converting enzyme inhibitors; hypertension..

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