Resumo

ADAMS-SANCHEZ, Christian David  e  TOBON-GARCIA, Gabriel Jaime. Monoclonal antibody therapy in Cardiology and Internal Medicine. Rev. Colomb. Cardiol. [online]. 2016, vol.23, n.4, pp.293-300. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2016.02.003.

The monoclonal antibodies (mAb) constitute a new therapeutic tool in cardiovascular medicine, based in the development of the molecular biology in this area. The understanding of therapeutic principles, types and mechanism of action of these drugs is essential for proper use and management of adverse reactions. We discuss the profile of the PCSK-9 inhibitors, the Dabigatran antidote, the abciximab, the digoxin antidote, the therapy in heart transplantation, and a possible cardiovascular use of monoclonal antibodies used in rheumatology.

Palavras-chave : Pharmacology; Immunology; Antibodies; Cardiovascular diseases; Low density lipoproteins cholesterol.

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