Resumo

RIBEIRO, Rodrigo Martins et al. Intratumumal application of eisplatin in the treatment of periocular sarcoid in equine. rev. colombiana cienc. anim. Recia [online]. 2022, vol.14, n.2, pp.52-58.  Epub 28-Mar-2023. ISSN 2027-4297.  https://doi.org/10.24188/recia.v14.n2.2022.919.

Equine sarcoid is a cutaneous neoplasm, with fibroblast, non-metastatic origin, locally invasive, responsible for even 66% of skin tumors in equines. Among treatments alternation, the use of intratumoral cisplatin after previous surgical excision is an option, with low recurrence rate. This study aims to report the case of a sarcoid located in the left supraorbital region of a mare and its treatment with intratumoral cisplatin. A mare was seen, tordilha, SRD, 5 years old and the weight of 280 Kg, presenting non-ulcerative volume increase in the left supraorbital region, with progressive evolution of 60 days. Neoplasm was suspected and lesion complete excision was made and forwarded to histopathological examination and sarcoid was diagnosed. Due to tumor recurrence, the second procedure was excision of tumor mass followed by chemotherapy treatment wtih 1mg/cm3 cisplatin dose of tumor mass. The drug was injected through intratumoral, during 4 applications, with two weeks breaks between every application. It was observed involution of the lesion right after the first dose until tumor's complete remission at the end of the treatment. The animal was seen during 7 months after the end of therapy and it was noted complete healing without sequels and relapses. It can be concluded that prognosis was favorable, and treatment proposed on this case report trough chemotherapy with intralesional cisplatin associated to surgical excision was effective.

Palavras-chave : Horse; neoplasia; chemotherapy.

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