Resumo

PARDO PEREZ, Enrique; CAVADIA MARTINEZ, Teodora Inés  e  CRUZ CANTERO, Andrea Estefanía. Genetic diversity in humans through Alu insertion polymorphisms in the population of San Pelayo, Córdoba- Colombia. LogosCyT [online]. 2019, vol.11, n.2, pp.86-92.  Epub 28-Dez-2019. ISSN 2145-594X.  https://doi.org/10.22335/rlct.v11i2.845.

This research determined the genetic diversity and population structure in human populations in San Pelayo, based on human Alu polymorphism. The samples were obtained from unrelated adults. The DNA of each sample was extracted using the PROMEGA kit, the markers were amplified by PCR and the amplified ones were subjected to electrophoresis and visualized in a transilluminator. The loci were polymorphic, the allelic frequencies showed heterogeneous values. The Hardy Weinberg test indicated that the population was not in equilibrium. Low heterozygosis and a high fixation index were also detected and the markers used were appropriate for the evaluation of genetic diversity. The population showed low diversity and a high polymorphic level.

Palavras-chave : Alu; genetic diversity; polymorphism; heterozygosis.

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