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Revista Colombiana de Gastroenterologia

Print version ISSN 0120-9957


CONTRERAS ZUNIGA, Eduardo; RAMIREZ CHEYNE, Julián Andrés; VALLEJO SERNA, Raúl Andrés  and  ZUNIGA CORREA, Leidy Patricia. Anemia perniciosa: descripción de un caso clínico. Rev Col Gastroenterol [online]. 2008, vol.23, n.1, pp.83-88. ISSN 0120-9957.

The anemia is characterized by a diminution in the concentration of hemoglobin or the capacity to transport oxygen in the blood. In the megaloblastic anemia a red diminution of the number of erythrocytes or globules takes place, and an increase in the size of such due to a deficiency of substances that take part in the eritropoyesis or formation of red globules, as it is the B12 vitamin. Nevertheless, the deficiency of this vitamin is secondary to the lack a protein of the gastric mucosa (intrinsic factor) this one yes basic one for its absorption. In these cases the intrinsic factor takes place and secret in minimum, insufficient amounts to make sure a normal intestinal absorption the vitamin or it does not take place absolutely.

Keywords : Pernicious anemia; B12 vitamin; megaloblastosis.

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