Abstract

GARCIA ROMO, Eduardo et al. Spinal cord compression due to nonleukemic granulocytic sarcoma. rev.colomb.cancerol. [online]. 2015, vol.19, n.4, pp.239-243. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2015.03.003.

Granulocytic sarcoma (GS) is an infrequent lesion associated with myelodysplastic or myeloproliferative disorders or leukemia, although it may be the first finding in an otherwise healthy patient. A case of GS is described that presented as spinal cord compression, in a patient with no underlying hematological disorder. Imaging studies disclosed a single lytic lesion in L1, which required emergency surgery. Immunohistochemical staining of the surgical biopsy sample was needed for diagnosis. Bone marrow aspirate was unremarkable. The patient received chemo-radiotherapy, dying 20 months after diagnosis of Pseudomonas aeruginosa sepsis during treatment of acute myelogenous leukemia. In short, primary GS is an infrequent and difficult to diagnose tumor. A high degree of suspicion, along with extensive immunohistochemical studies are necessary for diagnosis. Treatment should be prompt, aggressive and individualized, since the prognosis is very poor.

Keywords : Leukemia myeloid; Sarcoma myeloid; Low back pain; Chemotherapy; Radiotherapy.

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