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Perspectivas en Nutrición Humana

Print version ISSN 0124-4108


FUENTES-BARRIA, Héctor et al. Effects of Vitamin E Supplementation in Reducing Delayed Onset Muscle Pain. A Narrative Review. Perspect Nut Hum [online]. 2019, vol.21, n.2, pp.219-227.  Epub Dec 04, 2019. ISSN 0124-4108.


Currently, there is a growing interest in investigating methods that reduce delayed onset muscle pain. It has been postulated that antioxidants such as vitamin C and E can attenuate it.


To evaluate the effectiveness of vitamin E in mitigating delayed onset muscle pain.

Materials and Methods:

A bibliographic search was carried out in the following databases: Medline, Registry Central Cochrane, Scopus, SportDiscus and SciELO, using the terms: “vitamin e supplementation”, “muscle damage” and “delayed onset muscle soreness”.


Studies in diverse population groups were reviewed, with various evaluation methods and differing doses of vitamin E. The results were very controversial, in some cases a delayed onset pain effect was demonstrated and in other cases not.


Vitamin E produces a decrease in oxidative stress and stabilization of sarcolemma, however, conclusive evidence is lacking to state that vitamin E will have the effect of generating improvements in biomarkers associated with delayed onset muscle pain.

Keywords : Dietary supplements; vitamin E; tocopherols; antioxidants; muscle soreness.

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