Resumo

GUTIERREZ, Diego A; LOPEZ, José Julián; ACERO, Edward  e  HERNANDEZ, Orison Enrique. Prophylactic use of antibiotics in the medical-chirurgic unit of a Bogotá hospital. Rev. colomb. cienc. quim. farm. [online]. 2010, vol.39, n.1, pp.30-41. ISSN 0034-7418.

A descriptive cross-sectional study was carried-out in order to evaluate patterns of antimicrobial prophylaxis in surgery that they are continued in the Clinica Fundadores (CF) of Bogota city, classified in the third level of attention. The necessary information for the development of the study was obtained starting from secondary sources and it was gathered in a format designed for such purpose. 214 procedures were selected in a period of two months without previously infectious diagnosis and/or without antibiotics prescription for therapeutic reasons before de surgery. The assessment was developed on the basis of an algorithm that explains if the variables: indication prophylaxis, antimicrobial agent, dose, administration moment and postoperative regimen, are agree with previously selected national and international protocols. The results show that in several cases antimicrobial prophylaxis was not applied according with the recommendations of the protocols. Results shows administration of antibiotics when the prevention was not recommended (29.1%) and prolonging the prevention with postoperative dose when the recommendation is unique dose (65.2%), which evidences that the tendency in the clinic consists on the application of excessive prevention. The less proportion of errors are in the administration time. As conclusion, the study can affirm there are no unified criteria about the administration of antimicrobial prophylaxis in surgical procedures. The most frequent surgeries did in such period of time belong to gastrointestinal and traumatology specialties. The prophylaxis is oriented to the utilization of first generation cephalosporines and the combination gentamicin + clindamycin.

Palavras-chave : drug utilization; antibiotic prophylactics; pharmacoepidemiology.

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