Abstract

VEGA RUIZ, Erika Gilma; SANCHEZ, Ricardo  and  LOZANO, José Manuel. analysis of the incidence and resolution of the infection by the Human Papillomavirus in women undergoing a retrospective follow-up study. Rev. colomb. cienc. quim. farm. [online]. 2013, vol.42, n.2, pp.284-297. ISSN 0034-7418.

There are few longitudinal studies in Colombia that cover people from different parts of the country to allow understanding the infection dynamics by Human Papilloma Virus (HPV). A representative sample of 1433 women from three Colombian cities aged 18-60 years which were visited every 6 ± 2 months during two years, were submitted to the Papanicolau and reaction Polymerase chain (pcr) tests. Infection incidence was 2.49 /1000 women/day (CI 95%, 2.25-2.75), the incidence rate for lesion was 0.043 lesion/1000 women/day (CI 95%, 0.021-0.086), while for infection clearance the rate was 2.47 infection clearance/1000 women/day (CI 95%, 2.25-2.71). A women´s subgroup who reported having lesions on the first visit, had a rate of 3.92 lesion-regressions/1000 women/day (CI 95%, 2.97-5.17). From a group of 619 women with infection, 27% reported a persistent infection and only 10% of 55 women with cervical lesion kept this condition. Data showed that incidence and infection resolution was frequent, while the epidemiological study of lesions would require a greater number of women and a cohort of longer duration.

Keywords : HPV; incidence; infection clearance; lesion regression; persistence; rate..

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