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Revista Colombiana de Ciencias Químico - Farmacéuticas

versão impressa ISSN 0034-7418

Resumo

JOUYBAN, Abolghasem; PANAHI-AZA, Vahid; A.A. FAKHREE, Mohammad  e  AHMADIAN, Somaieh. Solubility of phenytoin in aqueous mixtures of ethanol and sodium dodecyl sulfate at 298 K. Rev. colomb. cienc. quim. farm. [online]. 2014, vol.43, n.1, pp.153-161. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v43n1.45470.

The solubility of phenytoin in binary mixtures of ethanol + water at 298.2 K in the presence of three different concentrations of sodium dodecyl sulfate (SDS) was reported. The Jouyban-Acree model was used for correlating the generated data and the obtained mean relative deviation was 7.3 %. When all data points of phenytoin in binary solvents at various SDS concentrations were fitted to the model, the obtained mean relative deviation was 10.1 %.

Palavras-chave : Solubility; phenytoin; ethanol; solvent mixture; sodium dodecyl sulfate; Jouyban-Acree model.

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