Abstract

HERNANDEZ-TORRES, José Eduardo  and  MELGOZA-CONTRERAS, Luz María. Major synthetic superdisintegrants, mechanisms and factors influencing their activity. Rev. colomb. cienc. quim. farm. [online]. 2014, vol.43, n.2, pp.234-247. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v43n2.54211.

Superdisintegrants have sparked some interest in terms of promoting greater bioavailability for certain drugs. Superdisintegrants are substances added to a formulation in order to break or disintegrate the tablet into smaller particles that dissolve more rapidly the active ingredient. This review shows an overview of their mechanisms of action, advantages and disadvantages and synthetic superdisintegrants currently most used

Keywords : oral route; tablets; disintegration mechanisms.

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